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Crosstalk between Thyroid Hormone Receptor and Liver X Receptor in the Regulation of Selective Alzheimer’s Disease Indicator-1 Gene Expression

Selective Alzheimer’s disease (AD) indicator 1 (Seladin-1) has been identified as a gene down-regulated in the degenerated lesions of AD brain. Up-regulation of Seladin-1 reduces the accumulation of β-amyloid and neuronal death. Thyroid hormone (TH) exerts an important effect on the development and...

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Autors principals: Ishida, Emi, Hashimoto, Koshi, Okada, Shuichi, Satoh, Tetsurou, Yamada, Masanobu, Mori, Masatomo
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554671/
https://ncbi.nlm.nih.gov/pubmed/23359226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0054901
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