Trehalose Maintains Bioactivity and Promotes Sustained Release of BMP-2 from Lyophilized CDHA Scaffolds for Enhanced Osteogenesis In Vitro and In Vivo

Calcium phosphate (Ca-P) scaffolds have been widely employed as a supportive matrix and delivery system for bone tissue engineering. Previous studies using osteoinductive growth factors loaded Ca-P scaffolds via passive adsorption often experience issues associated with easy inactivation and uncontr...

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Main Authors: Zhao, Jun, Wang, Shaoyi, Bao, Jianqiang, Sun, Xiaojuan, Zhang, Xiaochen, Zhang, Xiuli, Ye, Dongxia, Wei, Jie, Liu, Changsheng, Jiang, Xinquan, Shen, Gang, Zhang, Zhiyuan
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554655/
https://ncbi.nlm.nih.gov/pubmed/23359400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0054645
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