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GLP-1 and GLP-2 as Yin and Yang of Intestinal Lipoprotein Production: Evidence for Predominance of GLP-2–Stimulated Postprandial Lipemia in Normal and Insulin-Resistant States

The glucagon-like peptides (GLP-1 and GLP-2) are processed from the proglucagon polypeptide and secreted in equimolar amounts but have opposite effects on chylomicron (CM) production, with GLP-1 significantly reducing and GLP-2 increasing postprandial chylomicronemia. In the current study, we evalua...

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Main Authors: Hein, Gustavo J., Baker, Chris, Hsieh, Joanne, Farr, Sarah, Adeli, Khosrow
Format: Artigo
Jezik:Inglês
Izdano: American Diabetes Association 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554391/
https://ncbi.nlm.nih.gov/pubmed/23028139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db12-0202
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