Neuronal Androgen Receptor Regulates Insulin Sensitivity via Suppression of Hypothalamic NF-κB–Mediated PTP1B Expression

Clinical investigations highlight the increased incidence of metabolic syndrome in prostate cancer (PCa) patients receiving androgen deprivation therapy (ADT). Studies using global androgen receptor (AR) knockout mice demonstrate that AR deficiency results in the development of insulin resistance in...

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Detalhes bibliográficos
Main Authors: Yu, I-Chen, Lin, Hung-Yun, Liu, Ning-Chun, Sparks, Janet D., Yeh, Shuyuan, Fang, Lei-Ya, Chen, Lumin, Chang, Chawnshang
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2013
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554386/
https://ncbi.nlm.nih.gov/pubmed/23139353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db12-0135
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