A Vaccine Based on the Rhesus Cytomegalovirus UL128 Complex Induces Broadly Neutralizing Antibodies in Rhesus Macaques

Neutralizing antibodies (NAb) are important for interfering with horizontal transmission of human cytomegalovirus (HCMV) leading to primary and congenital HCMV infection. Recent findings have shown that a pentameric virion complex formed by the glycoproteins gH/gL, UL128, UL130, and UL131A (UL128C)...

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Detalhes bibliográficos
Main Authors: Wussow, Felix, Yue, Yujuan, Martinez, Joy, Deere, Jesse D., Longmate, Jeff, Herrmann, Andreas, Barry, Peter A., Diamond, Don J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554163/
https://ncbi.nlm.nih.gov/pubmed/23152525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01669-12
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