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Novel Mutations in gB and gH Circumvent the Requirement for Known gD Receptors in Herpes Simplex Virus 1 Entry and Cell-to-Cell Spread

Both entry and cell-to-cell spread of herpes simplex virus (HSV) involve a cascade of cooperative interactions among the essential glycoproteins D, B, and H/L (gD, gB, and gH/gL, respectively) initiated by the binding of gD to a cognate HSV entry receptor. We previously reported that a variant (D285...

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Detalhes bibliográficos
Main Authors: Uchida, Hiroaki, Chan, Janet, Shrivastava, Indira, Reinhart, Bonnie, Grandi, Paola, Glorioso, Joseph C., Cohen, Justus B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554156/
https://ncbi.nlm.nih.gov/pubmed/23152509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02804-12
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