Intramuscular Inoculation of Mice with the Live-Attenuated Recombinant Rabies Virus TriGAS Results in a Transient Infection of the Draining Lymph Nodes and a Robust, Long-Lasting Protective Immune Response against Rabies

A single intramuscular application of the live but not UV-inactivated recombinant rabies virus (RABV) variant TriGAS in mice induces the robust and sustained production of RABV-neutralizing antibodies that correlate with long-term protection against challenge with an otherwise lethal dose of the wil...

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Main Authors: Schutsky, Keith, Curtis, Dana, Bongiorno, Emily K., Barkhouse, Darryll A., Kean, Rhonda B., Dietzschold, Bernhard, Hooper, D. Craig, Faber, Milosz
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2013
Teme:
Vaccines and Antiviral Agents
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554143/
https://ncbi.nlm.nih.gov/pubmed/23192867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02589-12
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