hsp70 and a Novel Axis of Type I Interferon-Dependent Antiviral Immunity in the Measles Virus-Infected Brain

The major inducible 70-kDa heat shock protein (hsp70) is host protective in a mouse model of measles virus (MeV) brain infection. Transgenic constitutive expression of hsp70 in neurons, the primary target of MeV infection, abrogates neurovirulence in neonatal H-2(d) congenic C57BL/6 mice. A signific...

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Autors principals: Kim, Mi Young, Shu, Yaoling, Carsillo, Thomas, Zhang, Jianying, Yu, Lianbo, Peterson, Cornelia, Longhi, Sonia, Girod, Sarah, Niewiesk, Stefan, Oglesbee, Michael
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2013
Matèries:
Pathogenesis and Immunity
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554074/
https://ncbi.nlm.nih.gov/pubmed/23135720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02710-12
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