NIPP1 maintains EZH2 phosphorylation and promoter occupancy at proliferation-related target genes

The histone methyltransferase EZH2 regulates cell proliferation and differentiation by silencing Polycomb group target genes. NIPP1, a nuclear regulator of serine/threonine protein phosphatase 1 (PP1), has been implicated in the regulation of EZH2 occupancy at target loci, but the underlying mechani...

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Autores principales: Minnebo, Nikki, Görnemann, Janina, O’Connell, Nichole, Van Dessel, Nele, Derua, Rita, Vermunt, Marit Willemijn, Page, Rebecca, Beullens, Monique, Peti, Wolfgang, Van Eynde, Aleyde, Bollen, Mathieu
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2013
Materias:
Gene Regulation, Chromatin and Epigenetics
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3553949/
https://ncbi.nlm.nih.gov/pubmed/23241245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks1255
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