Rapid Detection of Panton-Valentine Leukocidin in Staphylococcus aureus Cultures by Use of a Lateral Flow Assay Based on Monoclonal Antibodies

Panton-Valentine leukocidin (PVL) is a virulence factor of Staphylococcus aureus, which is associated with skin and soft-tissue infections and necrotizing pneumonia. To develop a rapid phenotypic assay, recombinant PVL F component was used to generate monoclonal antibodies by phage display. These an...

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Main Authors: Monecke, Stefan, Müller, Elke, Buechler, Joseph, Rejman, John, Stieber, Bettina, Akpaka, Patrick Eberechi, Bandt, Dirk, Burris, Rob, Coombs, Geoffrey, Hidalgo-Arroyo, G. Aida, Hughes, Peter, Kearns, Angela, Abós, Sonia Molinos, Pichon, Bruno, Skakni, Leila, Söderquist, Bo, Ehricht, Ralf
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2013
Teme:
Bacteriology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3553917/
https://ncbi.nlm.nih.gov/pubmed/23175260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.02285-12
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