Epithelial Cells Augment Barrier Function via Activation of the Toll-Like Receptor 2/Phosphatidylinositol 3-Kinase Pathway upon Recognition of Salmonella enterica Serovar Typhimurium Curli Fibrils in the Gut

Curli fibrils, the best-characterized functional bacterial amyloids, are an important component of enterobacterial biofilms. We have previously shown that curli fibrils are recognized by the Toll-like receptor 2 (TLR2)/TLR1 heterodimer complex. Utilizing polarized T-84 cells, an intestinal epithelia...

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Détails bibliographiques
Auteurs principaux: Oppong, Gertrude O., Rapsinski, Glenn J., Newman, Tiffanny N., Nishimori, Jessalyn H., Biesecker, Steven G., Tükel, Çagla
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2013
Sujets:
Host Response and Inflammation
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3553802/
https://ncbi.nlm.nih.gov/pubmed/23208603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00453-12
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