TRIF Mediates Toll-Like Receptor 2-Dependent Inflammatory Responses to Borrelia burgdorferi

TRIF is an adaptor molecule important in transducing signals from intracellularly signaling Toll-like receptor 3 (TLR3) and TLR4. Recently, TLR2 was found to signal from intracellular compartments. Using a synthetic ligand for TLR2/1 heterodimers, as well as Borrelia burgdorferi, which is a strong a...

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Autors principals: Petnicki-Ocwieja, Tanja, Chung, Erin, Acosta, David I., Ramos, Laurie T., Shin, Ok S., Ghosh, Sanjukta, Kobzik, Lester, Li, Xin, Hu, Linden T.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2013
Matèries:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3553797/
https://ncbi.nlm.nih.gov/pubmed/23166161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00890-12
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