Identification of Gold Nanoparticle-Resistant Mutants of Saccharomyces cerevisiae Suggests a Role for Respiratory Metabolism in Mediating Toxicity

Positively charged gold nanoparticles (0.8-nm core diameter) reduced yeast survival, but not growth, at a concentration of 10 to 100 μg/ml. Among 17 resistant deletion mutants isolated in a genome-wide screen, highly significant enrichment was observed for respiration-deficient mutants lacking genes...

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Detalhes bibliográficos
Main Authors: Smith, Mark R., Boenzli, Matthew G., Hindagolla, Vihangi, Ding, Jun, Miller, John M., Hutchison, James E., Greenwood, Jeffrey A., Abeliovich, Hagai, Bakalinsky, Alan T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Genetics and Molecular Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3553748/
https://ncbi.nlm.nih.gov/pubmed/23144132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.01737-12
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