New Life for an Old Drug: the Anthelmintic Drug Niclosamide Inhibits Pseudomonas aeruginosa Quorum Sensing

The need for novel antibacterial strategies and the awareness of the importance of quorum sensing (QS) in bacterial infections have stimulated research aimed at identifying QS inhibitors (QSIs). However, clinical application of QSIs identified so far is still distant, likely due to their unsuitabili...

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Hlavní autoři: Imperi, Francesco, Massai, Francesco, Ramachandran Pillai, Cejoice, Longo, Francesca, Zennaro, Elisabetta, Rampioni, Giordano, Visca, Paolo, Leoni, Livia
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2013
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Mechanisms of Action: Physiological Effects
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3553739/
https://ncbi.nlm.nih.gov/pubmed/23254430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01952-12
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