Case-Control Study of Drug Monitoring of β-Lactams in Obese Critically Ill Patients

Severe sepsis and septic shock can alter the pharmacokinetics of broad-spectrum β-lactams (meropenem, ceftazidime/cefepime, and piperacillin-tazobactam), resulting in inappropriate serum concentrations. Obesity may further modify the pharmacokinetics of these agents. We reviewed our data on critical...

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Autori principali: Hites, Maya, Taccone, Fabio Silvio, Wolff, Fleur, Cotton, Frédéric, Beumier, Marjorie, De Backer, Daniel, Roisin, Sandrine, Lorent, Sophie, Surin, Rudy, Seyler, Lucie, Vincent, Jean-Louis, Jacobs, Frédérique
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2013
Soggetti:
Clinical Therapeutics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3553684/
https://ncbi.nlm.nih.gov/pubmed/23147743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01083-12
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