Impact of Pharmacogenetic Markers of CYP2B6, Clinical Factors, and Drug-Drug Interaction on Efavirenz Concentrations in HIV/Tuberculosis-Coinfected Patients

Comprehensive information on the effects of cytochrome P450 2B6 (CYP2B6) polymorphisms, clinical factors, and drug-drug interactions on efavirenz concentrations in HIV/tuberculosis-coinfected (HIV/TB) patients is unavailable. A total of 139 HIV/TB adults, 101 of whom received a rifampin-containing a...

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Autori principali: Manosuthi, Weerawat, Sukasem, Chonlaphat, Lueangniyomkul, Aroon, Mankatitham, Wiroj, Thongyen, Supeda, Nilkamhang, Samruay, Manosuthi, Sukanya, Sungkanuparph, Somnuek
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2013
Soggetti:
Clinical Therapeutics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3553682/
https://ncbi.nlm.nih.gov/pubmed/23254426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02023-12
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