In Vitro Activity of a New Oral Glucan Synthase Inhibitor (MK-3118) Tested against Aspergillus spp. by CLSI and EUCAST Broth Microdilution Methods

MK-3118, a glucan synthase inhibitor derived from enfumafungin, and comparator agents were tested against 71 Aspergillus spp., including itraconazole-resistant strains (MIC, ≥4 μg/ml), using CLSI and EUCAST reference broth microdilution methods. The CLSI 90% minimum effective concentration (MEC(90))...

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Autores principales: Pfaller, Michael A., Messer, Shawn A., Motyl, Mary R., Jones, Ronald N., Castanheira, Mariana
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2013
Materias:
Susceptibility
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3553681/
https://ncbi.nlm.nih.gov/pubmed/23229479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01588-12
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