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Effect of Ultraviolet Light on Mengovirus: Formation of Uracil Dimers, Instability and Degradation of Capsid, and Covalent Linkage of Protein to Viral RNA

UV irradiation of purified mengovirus resulted in a very rapid inactivation of the infectivity of the virions (D(37) [37% survival dose] = 700 ergs/mm(2)) which correlated in time with the formation of uracil dimers in the viral RNA. During the first 2 min of irradiation, an average of 1.7 uracil di...

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Bibliografiset tiedot
Julkaisussa:J Virol
Päätekijät: Miller, Richard L., Plagemann, Peter G. W.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology (ASM) 1974
Aiheet:
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC355360/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4132673/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.13.3.729-739.1974
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