Tumour-infiltrating FOXP3(+) lymphocytes are associated with cytotoxic immune responses and good clinical outcome in oestrogen receptor-negative breast cancer

BACKGROUND: Regulatory T cells (Tregs) are commonly identified by expression of the transcription factor FOXP3 and are conventionally thought to promote cancer progression by suppressing anti-tumour immune responses. We examined the relationship between FOXP3(+) tumour-infiltrating lymphocytes (TIL)...

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Hlavní autoři: West, N R, Kost, S E, Martin, S D, Milne, K, deLeeuw, R J, Nelson, B H, Watson, P H
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2013
Témata:
Molecular Diagnostics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3553524/
https://ncbi.nlm.nih.gov/pubmed/23169287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2012.524
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