Low-dose prednisone chronotherapy for rheumatoid arthritis: a randomised clinical trial (CAPRA-2)

OBJECTIVE: To assess the efficacy and safety of low-dose prednisone chronotherapy using a new modified-release (MR) formulation for the treatment of rheumatoid arthritis (RA). METHODS: In this 12-week, double-blind, placebo-controlled study, patients with active RA (n=350) were randomised 2:1 to rec...

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Detalhes bibliográficos
Main Authors: Buttgereit, Frank, Mehta, Daksha, Kirwan, John, Szechinski, Jacek, Boers, Maarten, Alten, Rieke E, Supronik, Jerzy, Szombati, Istvan, Romer, Ulrike, Witte, Stephan, Saag, Kenneth G
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2013
Assuntos:
Clinical and Epidemiological Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3553491/
https://ncbi.nlm.nih.gov/pubmed/22562974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2011-201067
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