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Targeting of Liposomes via PSGL1 for Enhanced Tumor Accumulation
PURPOSE: To improve the delivery of liposomes to tumors using P-selectin glycoprotein ligand 1 (PSGL1) mediated binding to selectin molecules, which are upregulated on tumorassociated endothelium. METHODS: PSGL1 was orientated and presented on the surface of liposomes to achieve optimal selectin bin...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Springer US
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3553414/ https://ncbi.nlm.nih.gov/pubmed/22992830 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-012-0875-5 |
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