Investigating Multiple Candidate Genes and Nutrients in the Folate Metabolism Pathway to Detect Genetic and Nutritional Risk Factors for Lung Cancer

PURPOSE: Folate metabolism, with its importance to DNA repair, provides a promising region for genetic investigation of lung cancer risk. This project investigates genes (MTHFR, MTR, MTRR, CBS, SHMT1, TYMS), folate metabolism related nutrients (B vitamins, methionine, choline, and betaine) and their...

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Detalhes bibliográficos
Main Authors: Swartz, Michael D., Peterson, Christine B., Lupo, Philip J., Wu, Xifeng, Forman, Michele R., Spitz, Margaret R., Hernandez, Ladia M., Vannucci, Marina, Shete, Sanjay
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3553105/
https://ncbi.nlm.nih.gov/pubmed/23372658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0053475
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