Autophagy-independent enhancing effects of Beclin 1 on cytotoxicity of ovarian cancer cells mediated by proteasome inhibitors

BACKGROUND: The ubiquitin-proteasome system and macroautophagy (hereafter referred to autophagy) are two complementary pathways for protein degradation. Emerging evidence suggests that proteasome inhibition might be a promising approach for tumor therapy. Accumulating data suggest that autophagy is...

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Detalhes bibliográficos
Main Authors: Liu, Chuan, Yan, Xu, Wang, Hua-Qin, Gao, Yan-Yan, Liu, Juanjuan, Hu, Zhenhua, Liu, Dawo, Gao, Jian, Lin, Bei
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3553022/
https://ncbi.nlm.nih.gov/pubmed/23270461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-12-622
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