A novel ER-localized transmembrane protein, EMC6, interacts with RAB5A and regulates cell autophagy

Autophagy is mediated by a unique organelle, the autophagosome, which encloses a portion of the cytoplasm for delivery to the lysosome. Phosphatidylinositol 3-phosphate (PtdIns3P) produced by the class III phosphatidylinositol 3-kinase (PtdIns3K) complex is essential for canonical autophagosome form...

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Hlavní autoři: Li, Yanjun, Zhao, Yuanbo, Hu, Jia, Xiao, Juan, Qu, Liujing, Wang, Zhenda, Ma, Dalong, Chen, Yingyu
Médium: Artigo
Jazyk:Inglês
Vydáno: Landes Bioscience 2013
Témata:
Basic Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3552880/
https://ncbi.nlm.nih.gov/pubmed/23182941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.22742
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