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Structure of histone mRNA stem-loop, human stem-loop binding protein and 3′hExo ternary complex

Metazoan replication-dependent histone mRNAs have a conserved stem-loop (SL) at their 3′-end. The stem–loop binding protein (SLBP) specifically recognizes the SL to regulate histone mRNA metabolism, and the 3′-5′ exonuclease 3′hExo trims its 3′-end after processing. We report the crystal structure o...

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Bibliografiske detaljer
Main Authors: Tan, Dazhi, Marzluff, William F., Dominski, Zbigniew, Tong, Liang
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3552377/
https://ncbi.nlm.nih.gov/pubmed/23329046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1228705
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