Cytoplasmic localization of alteration/deficiency in activation 3 (ADA3) predicts poor clinical outcome in breast cancer patients

Transcriptional activation by estrogen receptor (ER) is a key step to breast oncogenesis. Given previous findings that ADA3 is a critical component of HAT complexes that regulate ER function and evidence that overexpression of other ER coactivators such as SRC-3 is associated with clinical outcomes...

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Détails bibliographiques
Auteurs principaux: Mirza, Sameer, Rakha, Emad A., Alshareeda, Alaa, Mohibi, Shakur, Zhao, Xiangshan, Katafiasz, Bryan J., Wang, Jun, Gurumurthy, Channabasavaiah Basavaraju, Bele, Aditya, Ellis, Ian O., Green, Andrew R., Band, Hamid, Band, Vimla
Format: Artigo
Langue:Inglês
Publié: Springer US 2013
Sujets:
Preclinical Study
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3552361/
https://ncbi.nlm.nih.gov/pubmed/23288344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-012-2363-3
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