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Efficient Retrograde Transport of Pseudorabies Virus within Neurons Requires Local Protein Synthesis In Axons

After replicating in epithelial cells, alphaherpesviruses such as Pseudorabies Virus (PRV) invade axons of peripheral nervous system neurons and undergo retrograde transport toward the distant cell bodies. Although several viral proteins engage molecular motors to facilitate transport, the initial s...

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Detalhes bibliográficos
Main Authors: Koyuncu, Orkide O., Perlman, David H., Enquist, Lynn W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3552305/
https://ncbi.nlm.nih.gov/pubmed/23332155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2012.10.021
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