Preclinical Evaluation of HIV Eradication Strategies in the Simian Immunodeficiency Virus-Infected Rhesus Macaque: A Pilot Study Testing Inhibition of Indoleamine 2,3-Dioxygenase

Even in the setting of maximally suppressive antiretroviral therapy (ART), HIV persists indefinitely. Several mechanisms might contribute to this persistence, including chronic inflammation and immune dysfunction. In this study, we have explored a preclinical model for the evaluation of potential in...

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Bibliografiska uppgifter
Huvudupphovsmän: Dunham, Richard M., Gordon, Shari N., Vaccari, Monica, Piatak, Michael, Huang, Yong, Deeks, Steven G., Lifson, Jeffrey, Franchini, Genoveffa, McCune, Joseph M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Mary Ann Liebert, Inc. 2013
Ämnen:
Animal Studies
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3552181/
https://ncbi.nlm.nih.gov/pubmed/22924680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/aid.2012.0162
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