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Regulation of TLR2-mediated tolerance and cross-tolerance through IRAK4 modulation by miR-132/-212

Innate immune response is the first defense against pathogens via recognition by various conserved pattern recognition receptors, such as Toll-like receptors (TLRs), to initiate a rapid and strong cytokine alarm. TLR signaling-mediated cytokine production must be properly regulated to prevent pathol...

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Detalhes bibliográficos
Main Authors: Nahid, Md A, Yao, Bing, Dominguez-Gutierrez, Paul R, Satoh, Minoru, Chan, Edward K L
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3552145/
https://ncbi.nlm.nih.gov/pubmed/23264652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1103060
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