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A METABOLIC SIGNATURE FOR LONG-LIFE IN THE C. ELEGANS MIT MUTANTS

Mit mutations that disrupt function of the mitochondrial electron transport chain can, inexplicably, prolong Caenorhabditis elegans lifespan. In this study we use a metabolomics approach to identify an ensemble of mitochondrial-derived α-ketoacids and α-hydroxyacids that are produced by long-lived M...

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Detalhes bibliográficos
Main Authors: Butler, Jeffrey A., Mishur, Robert J., Bhaskaran, Shylesh, Rea, Shane L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3552119/
https://ncbi.nlm.nih.gov/pubmed/23173729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12029
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