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Exonuclease 1 Preferentially Repairs Mismatches Generated by DNA Polymerase α
The Saccharomyces cerevisiaeEXO1 gene encodes a 5′ exonuclease that participates in mismatch repair (MMR) of DNA replication errors. Deleting EXO1 was previously shown to increase mutation rates to a greater extent when combined with a mutator variant (pol3-L612M) of the lagging strand replicase, DN...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3552065/ https://ncbi.nlm.nih.gov/pubmed/23245696 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2012.11.001 |
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