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The effect of antigen encapsulation in chitosan particles on uptake, activation and presentation by antigen presenting cells

Particle-based vaccine delivery systems are under exploration to enhance antigen-specific immunity against safe but poorly immunogenic polypeptide antigens. Chitosan is a promising biomaterial for antigen encapsulation and delivery due to its ability to form nano- and microparticles in mild aqueous...

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Autores principales: Koppolu, Bhanu prasanth, Zaharoff, David A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3552013/
https://ncbi.nlm.nih.gov/pubmed/23274070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2012.11.066
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