Arsenic Exposure and Calpain-10 Polymorphisms Impair the Function of Pancreatic Beta-Cells in Humans: A Pilot Study of Risk Factors for T2DM

The incidence of type 2 diabetes mellitus (T2DM) is increasing worldwide and diverse environmental and genetic risk factors are well recognized. Single nucleotide polymorphisms (SNPs) in the calpain-10 gene (CAPN-10), which encodes a protein involved in the secretion and action of insulin, and chron...

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Main Authors: Díaz-Villaseñor, Andrea, Cruz, Laura, Cebrián, Arturo, Hernández-Ramírez, Raúl U., Hiriart, Marcia, García-Vargas, Gonzálo, Bassol, Susana, Sordo, Monserrat, Gandolfi, A. Jay, Klimecki, Walter T., López-Carillo, Lizbeth, Cebrián, Mariano E., Ostrosky-Wegman, Patricia
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3551951/
https://ncbi.nlm.nih.gov/pubmed/23349674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0051642
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