Pharmacological modulation of histone demethylase activity by a small molecule isolated from subcritical water extracts of Sasa senanensis leaves prolongs the lifespan of Drosophila melanogaster

BACKGROUND: Extracts of Sasa senanensis Rehder are used in traditional Japanese medicine; however, little is known about the underlying mechanisms of their potential health benefits. METHODS: S. senanensis leaves were extracted with subcritical water. An active small-molecule was isolated using reve...

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Detalhes bibliográficos
Main Authors: Nakagawa-Yagi, Yuzo, Sato, Yukiko, Matsumoto, Emi, Nakatsuka, Shin-ichi, Sakaki, Tsuyoshi, Muramatsu, Yukiko, Hara, Takaaki, Aigaki, Toshiro
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3551771/
https://ncbi.nlm.nih.gov/pubmed/22809229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6882-12-101
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