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Topological Variation in the Evolution of New Reactions in Functionally Diverse Enzyme Superfamilies
In functionally diverse enzyme superfamilies (SFs), conserved structural and active site features reflect catalytic capabilities “hard-wired” in each SF architecture. Overlaid on this foundation, evolutionary changes in active site machinery, structural topology and other aspects of structural organ...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3551608/ https://ncbi.nlm.nih.gov/pubmed/21458983 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2011.03.007 |
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