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Coexpression of Normally Incompatible Developmental Pathways in Retinoblastoma Genesis

It is widely believed that the molecular and cellular features of a tumor reflect its cell of origin and can thus provide clues about treatment targets. The retinoblastoma cell of origin has been debated for over a century. Here, we report that human and mouse retinoblastomas have molecular, cellula...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: McEvoy, Justina, Flores-Otero, Jacqueline, Zhang, Jiakun, Nemeth, Katie, Brennan, Rachel, Bradley, Cori, Krafcik, Fred, Rodriguez-Galindo, Carlos, Wilson, Matthew, Xiong, Shunbin, Lozano, Guillermina, Sage, Julien, Fu, Ligia, Louhibi, Lotfi, Trimarchi, Jeff, Pani, Amar, Smeyne, Richard, Johnson, Dianna, Dyer, Michael A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3551581/
https://ncbi.nlm.nih.gov/pubmed/21840489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2011.07.005
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