Furfural reduction mechanism of a zinc-dependent alcohol dehydrogenase from Cupriavidus necator JMP134

FurX is a tetrameric Zn-dependent alcohol dehydrogenase (ADH) from Cupriavidus necator JMP134. The enzyme rapidly reduces furfural with NADH as the reducing power. For the first time among characterized ADHs, the high-resolution structures of all reaction steps were obtained in a time-resolved manne...

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Hlavní autoři: Kang, ChulHee, Hayes, Robert, Sanchez, Emiliano J., Webb, Brian N., Li, Qunrui, Hooper, Travis, Nissen, Mark S., Xun, Luying
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3551575/
https://ncbi.nlm.nih.gov/pubmed/22081946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2011.07914.x
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