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The bZIP repressor proteins, c-Jun Dimerization Protein 2 and Activating Transcription Factor 3, recruit multiple HDAC members to the ATF3 promoter
JDP2, is a basic leucine zipper (bZIP) protein displaying a high degree of homology with the stress inducible transcription factor, ATF3. Both proteins bind to cAMP and TPA response elements and repress transcription by multiple mechanisms. Histone deacetylases (HDACs) play a key role in gene inacti...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3551276/ https://ncbi.nlm.nih.gov/pubmed/22989952 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagrm.2012.09.005 |
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