Endoscopic improvement of mucosal lesions in patients with moderate to severe ileocolonic Crohn's disease following treatment with certolizumab pegol

OBJECTIVE: To evaluate the efficacy of certolizumab pegol (CZP) in improving endoscopic lesions in patients with active ileocolonic Crohn's disease (CD). METHODS: This phase IIIB multicentre open-label clinical trial enrolled 89 adult patients with active endoscopic disease (ulceration in ≥2 in...

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Hlavní autoři: Hébuterne, Xavier, Lémann, Marc, Bouhnik, Yoram, Dewit, Olivier, Dupas, Jean-Louis, Mross, Michael, D'Haens, Geert, Mitchev, Krassimir, Ernault, Étienne, Vermeire, Séverine, Brixi-Benmansour, Hedia, Moreels, Tom G, Mary, Jean-Yves, Marteau, Philippe, Colombel, Jean-Frédéric
Médium: Artigo
Jazyk:Inglês
Vydáno: BMJ Group 2013
Témata:
Inflammatory Bowel Disease
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3551215/
https://ncbi.nlm.nih.gov/pubmed/22525883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2012-302262
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