Regulation of DNA-end resection by hnRNPU-like proteins promotes DNA double-strand break signaling and repair

DNA double-strand break (DSB) signaling and repair are critical for cell viability, and rely on highly coordinated pathways whose molecular organization is still incompletely understood. Here, we show that heterogeneous nuclear ribonucleoprotein U-like (hnRNPUL) proteins 1 and 2 play key roles in ce...

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Autori principali: Polo, Sophie E., Blackford, Andrew N., Chapman, J. Ross, Baskcomb, Linda, Gravel, Serge, Rusch, Andre, Thomas, Anoushka, Blundred, Rachel, Smith, Philippa, Kzhyshkowska, Julia, Dobner, Thomas, Taylor, A. Malcolm R., Turnell, Andrew S., Stewart, Grant S., Grand, Roger J., Jackson, Stephen P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3550743/
https://ncbi.nlm.nih.gov/pubmed/22365830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.12.035
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