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Dabigatran: Review of Pharmacology and Management of Bleeding Complications of This Novel Oral Anticoagulant

Dabigatran (Pradaxa) is a competitive direct thrombin inhibitor approved by the US FDA for prevention of embolic stroke in patients with nonvalvular atrial fibrillation. Dabigatran has a pharmacokinetic profile that produces predictable anticoagulation responses, does not undergo CYP 450 metabolism,...

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Detalhes bibliográficos
Main Authors: Ganetsky, Michael, Babu, Kavita M., Salhanick, Steven D., Brown, Robert S., Boyer, Edward W.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3550194/
https://ncbi.nlm.nih.gov/pubmed/21887485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13181-011-0178-y
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