A preliminary study for constructing a bioartificial liver device with induced pluripotent stem cell-derived hepatocytes

BACKGROUND: Bioartificial liver systems, designed to support patients with liver failure, are composed of bioreactors and functional hepatocytes. Immunological rejection of the embedded hepatocytes by the host immune system is a serious concern that crucially degrades the performance of the device....

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Main Authors: Iwamuro, Masaya, Shiraha, Hidenori, Nakaji, Shuhei, Furutani, Masumi, Kobayashi, Naoya, Takaki, Akinobu, Yamamoto, Kazuhide
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2012
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3549893/
https://ncbi.nlm.nih.gov/pubmed/23217363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-925X-11-93
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