Identification of differentially methylated regions using streptavidin bisulfite ligand methylation enrichment (SuBLiME), a new method to enrich for methylated DNA prior to deep bisulfite genomic sequencing

We have developed a method that enriches for methylated cytosines by capturing the fraction of bisulfite-treated DNA with unconverted cytosines. The method, called streptavidin bisulfite ligand methylation enrichment (SuBLiME), involves the specific labeling (using a biotin-labeled nucleotide ligand...

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Main Authors: Ross, Jason P., Shaw, Jan M., Molloy, Peter L.
פורמט: Artigo
שפה:Inglês
יצא לאור: Landes Bioscience 2013
נושאים:
Research Paper
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3549874/
https://ncbi.nlm.nih.gov/pubmed/23257838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.23330
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