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EGFR mutations are associated with favorable intracranial response and progression-free survival following brain irradiation in non-small cell lung cancer patients with brain metastases

BACKGROUND: The presence of epidermal growth factor receptor (EGFR) mutations in non-small cell lung cancer (NSCLC) is associated with increased radiosensitivity in vitro. However, the results from clinical studies regarding the radiosensitivity in NSCLC with mutant EGFR are inconclusive. We retrosp...

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Detalhes bibliográficos
Main Authors: Lee, Hsin-Lun, Chung, Tao-Sang, Ting, Lai-Lei, Tsai, Jo-Ting, Chen, Shang-Wen, Chiou, Jeng-Fong, Leung, Henry Wing-Cheung, Liu, H Eugene
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3549835/
https://ncbi.nlm.nih.gov/pubmed/23110940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1748-717X-7-181
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