The cell fate determinant Llgl1 influences HSC fitness and prognosis in AML

A unique characteristic of hematopoietic stem cells (HSCs) is the ability to self-renew. Several genes and signaling pathways control the fine balance between self-renewal and differentiation in HSCs and potentially also in leukemia stem cells. Recently, studies have shed light on developmental mole...

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Detalhes bibliográficos
Main Authors: Heidel, Florian H., Bullinger, Lars, Arreba-Tutusaus, Patricia, Wang, Zhu, Gaebel, Julia, Hirt, Carsten, Niederwieser, Dietger, Lane, Steven W., Döhner, Konstanze, Vasioukhin, Valera, Fischer, Thomas, Armstrong, Scott A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2013
Assuntos:
Brief Definitive Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3549713/
https://ncbi.nlm.nih.gov/pubmed/23277453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20120596
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