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Serum proteomics reveals systemic dysregulation of innate immunity in type 1 diabetes

Using global liquid chromatography-mass spectrometry (LC-MS)–based proteomics analyses, we identified 24 serum proteins that were significantly variant between those with type 1 diabetes (T1D) and healthy controls. Functionally, these proteins represent innate immune responses, the activation cascad...

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Detalhes bibliográficos
Main Authors: Zhang, Qibin, Fillmore, Thomas L., Schepmoes, Athena A., Clauss, Therese R.W., Gritsenko, Marina A., Mueller, Patricia W., Rewers, Marian, Atkinson, Mark A., Smith, Richard D., Metz, Thomas O.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3549705/
https://ncbi.nlm.nih.gov/pubmed/23277452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20111843
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