Changes in Fat Mitochondrial DNA and Function in Subjects Randomized to Abacavir-Lamivudine or Tenofovir DF–Emtricitabine With Atazanavir-Ritonavir or Efavirenz: AIDS Clinical Trials Group Study A5224s, Substudy of A5202

Background. The effect of nonthymidine nucleoside reverse-transcriptase inhibitors (NRTIs) on fat mitochondrial DNA (mtDNA) content and function is unclear. Methods. A5202 randomized antiretroviral therapy–naive human immunodeficiency virus–infected subjects to abacavir-lamivudine (ABC/3TC) versus t...

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Main Authors: McComsey, Grace A., Daar, Eric S., O'Riordan, MaryAnn, Collier, Ann C., Kosmiski, Lisa, Santana, Jorge L., Fichtenbaum, Carl J., Fink, Heidi, Sax, Paul E., Libutti, Daniel E., Gerschenson, Mariana
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2013
Assuntos:
Major Articles and Brief Reports
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3549598/
https://ncbi.nlm.nih.gov/pubmed/23204164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jis720
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