The Myosin Chaperone UNC-45 Is Organized in Tandem Modules to Support Myofilament Formation in C. elegans

The UCS (UNC-45/CRO1/She4) chaperones play an evolutionarily conserved role in promoting myosin-dependent processes, including cytokinesis, endocytosis, RNA transport, and muscle development. To investigate the protein machinery orchestrating myosin folding and assembly, we performed a comprehensive...

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Main Authors: Gazda, Linn, Pokrzywa, Wojciech, Hellerschmied, Doris, Löwe, Thomas, Forné, Ignasi, Mueller-Planitz, Felix, Hoppe, Thorsten, Clausen, Tim
Formato: Artigo
Idioma:Inglês
Publicado: Cell Press 2013
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3549490/
https://ncbi.nlm.nih.gov/pubmed/23332754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.12.025
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