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Identification of a cis-acting DNA–protein interaction implicated in singular var gene choice in Plasmodium falciparum

Plasmodium falciparum is responsible for the most severe form of malaria in humans. Antigenic variation of P. falciparum erythrocyte membrane protein 1 leads to immune evasion and occurs through switches in mutually exclusive var gene transcription. The recent progress in Plasmodium epigenetics notw...

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Detalhes bibliográficos
Main Authors: Brancucci, Nicolas M B, Witmer, Kathrin, Schmid, Christoph D, Flueck, Christian, Voss, Till S
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3549481/
https://ncbi.nlm.nih.gov/pubmed/22891919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cmi.12004
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