A Randomized, Controlled Pilot Study of Autologous CD34+ Cell Therapy for Critical Limb Ischemia

BACKGROUND: Critical limb ischemia (CLI) portends a risk of major amputation of 25-35% within 1 year of diagnosis. Pre-clinical studies provide evidence that intramuscular injection of autologous CD34+ cells improve limb perfusion and reduce amputation risk. In this randomized, double-blind, placebo...

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Detalhes bibliográficos
Main Authors: Losordo, Douglas W., Kibbe, Melina R., Mendelsohn, Farrell, Marston, William, Driver, Vickie R., Sharafuddin, Melhem, Teodorescu, Victoria, Wiechmann, Bret N., Thompson, Charles, Kraiss, Larry, Carman, Teresa, Dohad, Suhail, Huang, Paul, Junge, Candice E., Story, Kenneth, Weistroffer, Tara, Thorne, Tina M., Millay, Meredith, Runyon, John Paul, Schainfeld, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3549397/
https://ncbi.nlm.nih.gov/pubmed/23192920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCINTERVENTIONS.112.968321
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